Design of an Experiment
Undercoverage
– Undercoverage occurs when some groups in the population are left out of
the process of choosing the sample.
Matched
Pair Design – Matched pairs are a common form of blocking for comparing
just two treatments.
Stratified
Random Sample – To select a stratified random sample, first divide the
population into groups of similar individuals, called strata. Then choose a separate
simple random sample in each stratum and combine theses simple random samples to form a full sample.
Bias
– The design of a study is biased if it systematically favors certain
outcomes.
Treatment – A
specific experimental condition applied to the units is called a treatment.
Placebo – A placebo is a dummy treatment.
Control – The
group of patients who received a sham treatment is called a control group.
Statistically
Significant – An observed effect so large that it would rarely occur by chance is called statistically significant.
Completely
Randomized Design – When all experimental units are allocated at random among all treatments, the experimental design
is completely randomized.
Blind
Experiment – In a blind experiment, the subjects do not know which treatment
they received.
Double-Blind
Experiment – In a double-blind experiment, neither the subjects nor
the people who have contact with them know which treatment a subject received.
Block
Design – A block is a group of experimental units or subjects that are known before the experiment to be similar
in some way that is expected to affect the response to the treatments. In a block design, the random assignment of units to treatments is carried out separately
within each block.
Confounding
– Two variable are said to be confounded when their effects on a response
variable cannot be distinguished from each other.
Census – A census attempts to contact every individual in the entire population.
- A table
of random digits can be used for simulation as well as randomizing.
- In a matched
pair design, all subjects get both treatments in a random order.